suppressor factor

Background and Aim: Carcinoma is a type of multi-gene disease, and a complex process involved multi-factor, multi-stage and multi-gene mutation, which caused by activation of telomerase and cancer gene, devitalization of suppressor gene.

背景和目的：研究表明，肿瘤是一类多基因疾病，是由于端粒酶激活、癌基因激活或抑癌基因失活等引发的多因素、多阶段及多基因变异的综合病变过程。

As a complex process, infiltration and metastasis of malignant tumor is associated with motility, motility factor with its receptor, signal transduction, hereditary defect, tumor metastasis-related gene and tumor suppressor gene.

肿瘤的浸润和转移是一个复杂的过程，与肿瘤细胞的能动性、能动性因子及其受体、转移的信号转导、肿瘤细胞的遗传性缺陷、肿瘤转移相关基因及肿瘤抑制基因等诸多因素相关。

Objective To investigate the protective effects and mechanism of nuclear factor-kappa B ( NF-κ B) suppressor& pyrrolidine thiocarbamate ( PDTC) on lung injury caused by mechanical ventilation and endotoxin.

目的探讨NF-κB抑制剂吡咯烷二硫代氨基甲酸盐（pyrrolidine thiocarbamate，PDTC）对机械通气及机械通气复合内毒素肺损伤的保护作用及其机制。